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扩大免疫规划中大规模免疫接种运动的应用:已报道的利弊综述

The use of mass campaigns in the expanded program on immunization: a review of reported advantages and disadvantages.

作者信息

Dietz V, Cutts F

机构信息

Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341-3724, USA.

出版信息

Int J Health Serv. 1997;27(4):767-90. doi: 10.2190/QPCQ-FBF8-6ABX-2TB5.

Abstract

The use of mass immunization campaigns (MICs) has been and remains controversial. To evaluate these campaigns, the authors review the literature relating to their effectiveness, sustainability, and cost-effectiveness in controlling diseases and raising immunization coverage levels, and their impact on the subsequent development of routine immunization services. Well-conducted campaigns have increased vaccine coverage levels and decreased disease morbidity and mortality. Their use in the Americas has been associated with the apparent elimination of poliomyelitis. However, unless health care infrastructure is improved, or campaigns are repeated, gains in coverage levels may not be sustained. Studies suggest that MICs are often not as cost-effective for raising coverage as the delivery of vaccines through routine services, but the use of coverage as the only outcome measure is questionable. Mass immunization campaigns can increase awareness of vaccination and may be appropriate in situations where new programs are to be initiated, in refugee situations where people congregate into areas with little infrastructure, and in disease eradication efforts when specific time goals are set. Little information is available on whether MICs strengthen or interfere with the development of routine services. To be successful, MICs require a well-coordinated and planned effort on the part of national authorities with the identification of specific goals, intensive social promotion, and strong management. In addition, research is needed to clarify how MICs should be evaluated.

摘要

大规模免疫接种运动(MICs)的使用一直存在争议且仍备受争议。为评估这些运动,作者回顾了有关其在控制疾病和提高免疫接种覆盖率方面的有效性、可持续性和成本效益,以及它们对常规免疫服务后续发展的影响的文献。组织良好的运动提高了疫苗接种覆盖率,降低了疾病发病率和死亡率。在美洲,其使用与明显消除脊髓灰质炎有关。然而,除非改善卫生保健基础设施或重复开展运动,覆盖率的提高可能无法持续。研究表明,通过大规模免疫接种运动提高覆盖率的成本效益通常不如通过常规服务提供疫苗,但将覆盖率作为唯一的结果衡量指标是值得怀疑的。大规模免疫接种运动可以提高对疫苗接种的认识,在启动新计划的情况下、在人们聚集到基础设施薄弱地区的难民情况下以及在设定特定时间目标的疾病根除工作中可能是合适的。关于大规模免疫接种运动是加强还是干扰常规服务的发展,几乎没有可用信息。要取得成功,大规模免疫接种运动需要国家当局进行协调良好和有计划的努力,确定具体目标、进行密集的社会宣传并加强管理。此外,需要开展研究以阐明应如何评估大规模免疫接种运动。

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