Hills J R, Cardella J F, Cardella K, Waybill P N
Department of Radiology, The Pennsylvania State University Hospital, Hershey 17033, USA.
J Vasc Interv Radiol. 1997 Nov-Dec;8(6):983-9. doi: 10.1016/s1051-0443(97)70698-5.
This study reports the authors' experience with long-term follow-up of 100 consecutive peripherally inserted, subcutaneous arm ports for central venous access.
One hundred patients with subcutaneous arm ports inserted by interventional radiologists were retrospectively studied. Data were collected from the patients' medical records and from telephone canvassing. Using each insertion period as an observation, the complication rates per 100 catheter days were determined with 95% confidence intervals (CIs).
One hundred subcutaneously implanted ports were placed in 98 patients; three devices (three patients) were lost to follow-up, leaving 97 devices in 95 patients. Total exposure time was 23,842 days (mean, 246 days; range, 2-865 days). Seven infectious and two noninfectious complications occurred with seven (7.2%) devices in six patients (6.3%), yielding 0.038 complications per 100 catheter days at risk (95% CI; 0.011-0.069) and 0.029 infections per 100 catheter days at risk (95% CI; 0.008-0.058). A successful clinical outcome was defined as a functional port at removal, time of death, or at study closure (minimum of 6 months of follow-up), which was not removed because of a complication. This successful outcome was achieved in 91 ports (93.8%). Procedural-related complications, defined as those occurring up to 30 days after insertion, occurred in only one port (thrombophlebitis and catheter tip infection-day 9). All other patients received several months of service from their port. Fifteen devices were placed in 13 patients with HIV for 3,486 days, with a total complication rate of 0.11 per 100 catheter days (95% CI; 0.0-0.28), all of which were infections. Devices in HIV-positive patients were associated with higher total complication (20% vs 4.9%) and infection rates (20% vs 3.7%) than devices in patients without HIV infection. This gives a relative risk 8.17 x (P = .04) greater for infectious complications for devices placed in HIV-infected individuals.
Subcutaneous arm ports placed by interventional radiologists are effective for central venous access with excellent functionality (93.8% achieved a successful long-term outcome) and a very low procedural complication rate. Although infections were more frequent in HIV-infected individuals, these devices are associated with a very low incidence of both immediate and long-term complications, including infection, for all patients.
本研究报告了作者对100例连续经外周插入的皮下手臂端口进行中心静脉通路长期随访的经验。
对100例由介入放射科医生插入皮下手臂端口的患者进行回顾性研究。数据从患者病历和电话随访中收集。以每个插入期作为观察期,确定每100导管日的并发症发生率及95%置信区间(CI)。
98例患者植入了100个皮下端口;3个装置(3例患者)失访,95例患者中剩余97个装置。总暴露时间为23842天(平均246天;范围2 - 865天)。6例患者(6.3%)的7个装置(7.2%)发生了7例感染性并发症和2例非感染性并发症,每100导管日的风险并发症发生率为0.038(95%CI:0.011 - 0.069),每100导管日的风险感染率为0.029(95%CI:0.008 - 0.058)。成功的临床结局定义为在拔除、死亡或研究结束时(至少6个月随访)功能正常的端口,且未因并发症而拔除。91个端口(93.8%)实现了这一成功结局。与操作相关的并发症定义为插入后30天内发生的并发症,仅1个端口发生(第9天血栓性静脉炎和导管尖端感染)。所有其他患者的端口使用了数月。13例HIV患者的15个装置使用了3486天,每100导管日的总并发症发生率为0.11(95%CI:0.0 - 0.28),均为感染。HIV阳性患者的装置与无HIV感染患者的装置相比,总并发症(20%对4.9%)和感染率(20%对3.7%)更高。这使得HIV感染个体植入装置发生感染性并发症的相对风险高8.17倍(P = 0.04)。
介入放射科医生植入的皮下手臂端口用于中心静脉通路有效,功能良好(93.8%实现了长期成功结局)且操作并发症发生率极低。尽管HIV感染个体感染更频繁,但这些装置对所有患者而言,即时和长期并发症(包括感染)的发生率都很低。