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髋部骨折后长期入住养老院的临床预测规则的制定与验证

Development and validation of a clinical prediction rule for prolonged nursing home residence after hip fracture.

作者信息

Steiner J F, Kramer A M, Eilertsen T B, Kowalsky J C

机构信息

Center for Health Services Research, University of Colorado Health Sciences Center, Denver, USA.

出版信息

J Am Geriatr Soc. 1997 Dec;45(12):1510-4. doi: 10.1111/j.1532-5415.1997.tb03204.x.

DOI:10.1111/j.1532-5415.1997.tb03204.x
PMID:9400563
Abstract

OBJECTIVES

To develop and validate a clinical prediction rule for nursing home residence 6 months after a hip fracture.

DESIGN

Two prospective cohort studies, a development study (DS) and a validation study (VS).

SETTING

The DS included hip fracture patients admitted to 92 rehabilitation units or skilled nursing facilities; the VS included hip fracture patients from 11 integrated healthcare systems.

PARTICIPANTS

A total of 344 community-dwelling hip fracture patients aged 65 and older participated in the DS; 239 similar patients were enrolled in the VS.

INTERVENTION

None.

MEASUREMENTS

The acute hospital record, nursing evaluations, and patient questionnaires provided information about demographics, physical and neuropsychological function, and comorbidity. Residence 6 months after fracture was determined by phone interview. Multivariate analysis identified predictors for a risk score to assess the likelihood of nursing home residence.

RESULTS

18.7% of patients in the DS resided in nursing homes 6 months after hip fracture. The four independent risk factors for institutionalization were (1) being unmarried (OR = 6.7 [95% CI 2.4 to 19]), (2) incontinence (OR = 2.3 [CI 1.2 to 4.7]), (3) dependence in ambulation (OR = 5.0 [CI 2.1 to 12.3]), and (4) cognitive impairment (OR = 6.6 [CI 3.3 to 13.2]). Of patients with all four risk factors, 73.2% were institutionalized at 6 months, compared with 0% of patients with no risk factors. In the VS, 6.1% of patients resided in nursing homes after 6 months, with a range from 50.0% of patients with four risk factors to 0% of those with no risk factors. Areas under receiver-operating characteristic curves for the prediction rule were 0.84 +/- .03 in the DS, and 0.81 +/- .06 in the VS.

CONCLUSION

A clinical prediction rule using four easily measurable characteristics can identify individuals at high or low risk of nursing home residence 6 months after hip fracture.

摘要

目的

制定并验证一项关于髋部骨折后6个月入住养老院情况的临床预测规则。

设计

两项前瞻性队列研究,一项开发研究(DS)和一项验证研究(VS)。

设置

开发研究纳入了92个康复单元或专业护理机构收治的髋部骨折患者;验证研究纳入了11个综合医疗系统的髋部骨折患者。

参与者

共有344名65岁及以上的社区居住髋部骨折患者参与了开发研究;239名类似患者纳入了验证研究。

干预措施

无。

测量指标

急性医院病历、护理评估和患者问卷提供了有关人口统计学、身体和神经心理功能以及合并症的信息。通过电话访谈确定骨折后6个月的居住情况。多变量分析确定了用于风险评分的预测因素,以评估入住养老院的可能性。

结果

开发研究中18.7%的患者在髋部骨折后6个月入住养老院。入住养老院的四个独立风险因素为:(1)未婚(比值比[OR]=6.7[95%置信区间(CI)2.4至19]),(2)失禁(OR=2.3[CI 1.2至4.7]),(3)行走依赖(OR=5.0[CI 2.1至12.3]),以及(4)认知障碍(OR=6.6[CI 3.3至13.2])。具有所有四个风险因素的患者中,73.2%在6个月时入住养老院,而无风险因素的患者这一比例为0%。在验证研究中,6.1%的患者在6个月后入住养老院,有四个风险因素的患者比例为50.0%,无风险因素的患者比例为0%。预测规则在开发研究中的受试者工作特征曲线下面积为0.84±0.03,在验证研究中为0.81±0.06。

结论

一项使用四个易于测量特征的临床预测规则能够识别髋部骨折后6个月入住养老院风险高或低的个体。

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