State M W, King B H, Dykens E
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, USA.
J Am Acad Child Adolesc Psychiatry. 1997 Dec;36(12):1664-71. doi: 10.1097/00004583-199712000-00014.
To review the literature over the past decade on mental retardation, particularly with respect to genetics and behavioral phenotypes.
A computerized search was performed for articles published in the past decade, and selected papers were highlighted.
The study of mental retardation has benefited considerably by advances in medicine generally, and by developments in molecular neurobiology in particular. These advances in genetics have led to new insights regarding the causes of mental retardation, as well as a growing appreciation of behavioral phenotypes associated with some mental retardation syndromes.
Although the study of developmental disorders has advanced significantly over the past decade, considerable work remains. Mental retardation should remain the model for the utility of the biopsychosocial approach in medicine.
回顾过去十年间关于智力迟钝的文献，尤其关注遗传学和行为表型方面。
对过去十年发表的文章进行计算机检索，并突出显示选定的论文。
医学领域的总体进步，特别是分子神经生物学的发展，使智力迟钝的研究受益匪浅。遗传学的这些进展为智力迟钝的病因带来了新的见解，同时也使人们越来越认识到与某些智力迟钝综合征相关的行为表型。
尽管发育障碍的研究在过去十年中有了显著进展，但仍有大量工作要做。智力迟钝应继续作为生物心理社会方法在医学中应用的典范。
