Connell P H, Christie D J, May W W
J Med Ethics. 1976 Jun;2(2):87-92.
An experiment is described in which three male volunteers, who fully understood the nature of the project, were given doses of heroin which could have led to addiction if the subjects had proved to be physiologically or psychologically vulnerable to developing a state of addiction. The experiment was discussed most carefully by the Ethics Committee of the unit where it was conducted, and the subjects were themselves the investigators. The objective was to learn about the initial stages of the adaptation to heroin, of which nothing was known as heroin addicts usually come to the doctor when the habit is firmly established. A physician, who has studied the subject of drug addiction in a special clinic, is the first commentator, the second a lawyer and the third an associate professor of social ethics. These three experts are not discussing the results or the methodology of the experiment but whether the decision of the Ethics Committe was the right one.
描述了一项实验，在该实验中，三名完全理解项目性质的男性志愿者被给予了海洛因剂量，如果这些受试者在生理或心理上被证明易成瘾，那么这些剂量本可能导致成瘾。进行该实验的单位伦理委员会对其进行了极为仔细的讨论，而受试者本身就是研究者。目的是了解对海洛因适应的初始阶段，因为对于这方面一无所知，通常海洛因成瘾者在毒瘾牢固确立后才会去看医生。一位在一家特殊诊所研究药物成瘾课题的医生是第一位评论者，第二位是律师，第三位是社会伦理学副教授。这三位专家并非在讨论实验结果或方法，而是讨论伦理委员会的决定是否正确。
