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巨大骶管内神经鞘瘤:6例报告

Giant intrasacral schwannomas: report of six cases.

作者信息

Domínguez J, Lobato R D, Ramos A, Rivas J J, Gómez P A, Castro S

机构信息

Department of Neurosurgery, Hospital 12 de Octubre, Madrid, Spain.

出版信息

Acta Neurochir (Wien). 1997;139(10):954-9; discussion 959-60. doi: 10.1007/BF01411305.

Abstract

Only 4 of the 30 previously reported cases of giant sacral schwannomas have been studied with Magnetic Resonance Imaging (MRI). We are reporting 6 more cases, 5 of which had MRI studies. There were 5 women and 1 man (average age 45 years) with long lasting symptoms consisting of lumbosacral and radicular pain accompanied by urinary disturbances and dysaesthetic sensations in the lower limbs. CT clearly defined sacral bone involvement but poorly demonstrated intraspinal tumour extension which was more evident in MRI studies. MRI also clearly showed the intrapelvic extension of the tumour, its relationship with the neighbouring structures and the dumbbell growth pattern due to tumour extension through sacral foramina which are important data for making a pro-operative diagnosis and surgical planning. Surgical treatment consisted of piecemeal tumour resection through a posterior approach in four cases. Two patients underwent operation through an abdominal transperitoneal approach followed by a sacral laminectomy. Total intracapsular resection was apparently achieved in 5 cases. Through an average follow-up period of 9.2 years and despite a rather conservative approach, the recurrence rate has been very low in our series and only one patient had to be re-operated on for tumour recurrence.

摘要

在先前报道的30例巨大骶骨神经鞘瘤病例中,仅有4例接受了磁共振成像(MRI)检查。我们现报告另外6例,其中5例进行了MRI检查。患者中有5名女性和1名男性(平均年龄45岁),有长期症状,包括腰骶部和神经根性疼痛,并伴有泌尿系统紊乱和下肢感觉异常。CT能清晰显示骶骨受累情况,但对椎管内肿瘤扩展的显示较差,而这在MRI检查中更为明显。MRI还清晰显示了肿瘤在盆腔内的扩展、其与邻近结构的关系以及由于肿瘤通过骶孔扩展而形成的哑铃状生长模式,这些都是术前诊断和手术规划的重要数据。4例患者通过后路进行了肿瘤分块切除手术治疗。2例患者通过经腹经腹膜途径手术,随后进行骶骨椎板切除术。显然,5例实现了肿瘤囊内全切。经过平均9.2年的随访,尽管采取了较为保守的方法,但我们系列中的复发率非常低,只有1例患者因肿瘤复发需要再次手术。

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