Gulani V, Iwamoto G A, Jiang H, Shimony J S, Webb A G, Lauterbur P C
Department of Molecular and Integrative Physiology, College of Medicine, University of Illinois at Urbana-Champaign, Urbana 61801, USA.
Magn Reson Med. 1997 Dec;38(6):868-73. doi: 10.1002/mrm.1910380603.
A new imaging sequence for rapid determination of the apparent self-diffusion tensor of water was developed and tested on fixed excised rat spinal cords. To reduce the time required to determine the tensor, the sequence utilized a new single-shot approach with multiple spin echoes. An assumption of cylindrical symmetry in the sample was made, thus requiring the measurement of only four of the six unique elements of the tensor. This assumption was found experimentally to be valid, and the results obtained using the new sequence were found to be quantitatively the same as results obtained using a standard spin-echo sequence.
开发了一种用于快速测定水的表观自扩散张量的新成像序列，并在固定的大鼠脊髓标本上进行了测试。为了减少测定张量所需的时间，该序列采用了一种带有多个自旋回波的新型单次激发方法。假设样本具有圆柱对称性，因此只需要测量张量六个独立元素中的四个。通过实验发现该假设是有效的，并且使用新序列获得的结果在定量上与使用标准自旋回波序列获得的结果相同。
