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晚年重度和轻度抑郁症的后果:一项关于残疾、幸福感和服务利用情况的研究。

Consequences of major and minor depression in later life: a study of disability, well-being and service utilization.

作者信息

Beekman A T, Deeg D J, Braam A W, Smit J H, Van Tilburg W

机构信息

Department of Psychiatry, Free University, Amsterdam, The Netherlands.

出版信息

Psychol Med. 1997 Nov;27(6):1397-409. doi: 10.1017/s0033291797005734.

Abstract

BACKGROUND

The consequences of major depression for disability, impaired well-being and service utilization have been studied primarily in younger adults. In all age groups the consequences of minor depression are virtually unknown. In later life, the increased co-morbidity with physical illness may modify the consequences of depression, warranting special study of the elderly. With rising numbers of elderly people, excess service utilization by depressed elderly represents an increasingly important issue.

METHODS

Based on a large, random community-based sample of older inhabitants of the Netherlands (55-85 years), the associations of major and minor depression with various indicators of disability, well-being and service utilization were assessed, controlling for potential confounding factors. Depression was diagnosed using a two-stage screening design. Diagnosis took place in all subjects with high depressive symptom levels and a random sample of those with low depressive symptom levels. The study sample consists of all participants to diagnostic interviews (N = 646).

RESULTS

As in younger adults, associations of both major and minor depression with disability and well-being remained significant after controlling for chronic disease and functional limitations. Adequate treatment is often not administered, even in subjects with major depression. As the vast majority of those depressed were recently seen by their general practitioners, treatment could have been provided in most cases. Bivariate analyses show that major and minor depression are associated with an excess use of non-mental health services, underscoring the importance of recognition. In multivariate analyses the evidence of excess service utilization was less compelling.

CONCLUSIONS

Both major and minor depression are consequential for well-being and disability, supporting efforts to improve the recognition and treatment in primary care. However, controlled trials are necessary to assess the impact this may have on service utilization.

摘要

背景

重度抑郁症对残疾、幸福感受损及服务利用的影响主要在年轻成年人中进行了研究。在所有年龄组中,轻度抑郁症的影响几乎无人知晓。在晚年,与躯体疾病共病率的增加可能会改变抑郁症的影响,因此有必要对老年人进行专门研究。随着老年人数量的增加,抑郁老年人的服务利用过度成为一个日益重要的问题。

方法

基于荷兰大量随机抽取的55 - 85岁社区老年居民样本,评估了重度和轻度抑郁症与残疾、幸福感及服务利用的各种指标之间的关联,并对潜在的混杂因素进行了控制。抑郁症采用两阶段筛查设计进行诊断。对所有抑郁症状水平高的受试者以及抑郁症状水平低的受试者的随机样本进行诊断。研究样本包括所有接受诊断访谈的参与者(N = 646)。

结果

与年轻成年人一样,在控制了慢性病和功能限制后,重度和轻度抑郁症与残疾及幸福感之间的关联仍然显著。即使在重度抑郁症患者中,也常常没有给予充分的治疗。由于绝大多数抑郁患者最近都看过全科医生,在大多数情况下本可以提供治疗。双变量分析表明,重度和轻度抑郁症与非心理健康服务的过度使用有关,这突出了识别的重要性。在多变量分析中,服务利用过度的证据不那么有说服力。

结论

重度和轻度抑郁症都会影响幸福感和导致残疾,这支持了在初级保健中改善识别和治疗的努力。然而,需要进行对照试验来评估这可能对服务利用产生的影响。

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