Kasama S, Hayafuji M, Takano T, Songhee K, Ogihara M, Nishizawa M, Ishida F, Sodeyama H
Department of Anesthesiology, Nagano Red Cross Hospital.
Masui. 1997 Nov;46(11):1496-8.
A 56-year-old female with macrothrombocytopenia was scheduled for colectomy and hepatectomy. She had not shown significant bleeding tendency. Her preoperative platelet counts were 0.5-1.6 x 10(4) microliters-1 with the use of an automated cell counter. However, microscopic examination showed platelet number ranging 0.9-3.4 x 10(4) microliters-1 and many macrothrombocytes. Therefore, platelet biomass (platelet number x platelet volume) seemed almost normal. Bleeding time was 3 minutes and platelet function was normal. She received preoperatively high dose gamma-globulin administration and intraoperatively platelet transfusion. The operation was performed under combined epidural and general anesthesia. Intra- and post-operative course was uneventful.
一名患有巨血小板减少症的56岁女性计划接受结肠切除术和肝切除术。她没有明显的出血倾向。使用自动血细胞计数器检测，其术前血小板计数为0.5 - 1.6×10⁴/微升。然而，显微镜检查显示血小板数量在0.9 - 3.4×10⁴/微升之间，且有许多巨血小板。因此，血小板生物量（血小板数量×血小板体积）似乎基本正常。出血时间为3分钟，血小板功能正常。她术前接受了大剂量丙种球蛋白治疗，术中输注了血小板。手术在硬膜外麻醉和全身麻醉联合下进行。术中和术后过程顺利。
