Arvanitogiannis A, Flores C, Shizgal P
Department of Psychology, Concordia University, West Montréal, Qué, Canada.
Behav Brain Res. 1997 Nov;88(2):275-9. doi: 10.1016/s0166-4328(97)00065-x.
Fos immunohistochemistry was used to stain neurons in the caudal diencephalon, midbrain and hindbrain driven by rewarding stimulation of the lateral hypothalamus (LH). Increases in Fos-like immunoreactivity were most pronounced ipsilateral to the site of stimulation and tended to be confined within discrete structures such as the posterior LH, arcuate nucleus, ventral tegmental area (VTA), central gray, dorsal raphé, pedunculopontine area (PPTg), parabrachial nucleus, and locus coeruleus. At least two of these structures, the VTA and PPTg, have been implicated in medial forebrain bundle self-stimulation.
采用Fos免疫组织化学法对受下丘脑外侧区（LH）奖赏性刺激驱动的尾侧间脑、中脑和后脑神经元进行染色。Fos样免疫反应性增加在刺激部位同侧最为明显，并且倾向于局限在离散结构内，如LH后部、弓状核、腹侧被盖区（VTA）、中央灰质、中缝背核、脚桥被盖区（PPTg）、臂旁核和蓝斑。这些结构中至少有两个，即VTA和PPTg，与内侧前脑束自我刺激有关。
