Lane D W, Peach D F
School of Engineering and Applied Science, Cranfield University, RMCS, Wiltshire, UK.
Biol Trace Elem Res. 1997 Oct-Nov;60(1-2):1-11. doi: 10.1007/BF02783305.
The concentration of trace elements has been measured for dental enamel from 86 healthy human teeth using particle-induced X-ray emission (PIXE). The majority of the teeth (n = 70) were collected from dentists in the county of Oxfordshire in the United Kingdom, although a smaller group (n = 16) were collected from Cornwall. The elements K, Ca, Mn, Fe, Co, Ni, Cu, Zn, Sr, Pb, and Hg have been detected and statistically analyzed by grouping according to sex, age, and geographical location. The concentrations of Fe and Cu were found to be lower in the teeth from female donors (P < 5%) and are believed to result from the continued burden of blood loss during menstruation. Strong positive correlations (P < 0.1%) were found between Ca, Co, Ni, and Zn for all groups; these elements were also found to exhibit a negative correlation (P < 1%) with age for teeth from female donors. This is believed to be related to decalcification during the menopause. Pb was found to exhibit a positive correlation (P < 5%) with age for both sexes, and is believed to substitute for Ca in the Ca hydroxy apatite (HAP) within the dental enamel.
利用粒子诱导X射线发射（PIXE）技术测量了86颗健康人牙齿牙釉质中的微量元素浓度。大多数牙齿（n = 70）采集自英国牛津郡的牙医处，不过有一小部分（n = 16）采集自康沃尔郡。已检测出钾、钙、锰、铁、钴、镍、铜、锌、锶、铅和汞等元素，并根据性别、年龄和地理位置进行分组统计分析。发现女性捐赠者牙齿中的铁和铜浓度较低（P < 5%），据信这是由于月经期间持续失血所致。所有组中钙、钴、镍和锌之间均存在强正相关（P < 0.1%）；还发现这些元素与女性捐赠者牙齿的年龄呈负相关（P < 1%）。据信这与更年期期间的脱钙有关。发现铅在两性中均与年龄呈正相关（P < 5%），据信它会在牙釉质中的羟基磷灰石（HAP）中替代钙。
