Zubac D P, Kihl B
Department of Surgery, Central Hospital, Karlstad, Sweden.
Scand J Urol Nephrol. 1997 Oct;31(5):435-8. doi: 10.3109/00365599709030637.
A retrospective study was carried out on 20 patients with transitional cell ureteral tumours (TCUT). Surgical exploration of the tumour was performed in 17 patients. Biopsies for frozen section were evaluated for decision concerning the extent of operative intervention. If radical excision of the tumour could be done, and if the ureteral defect could be bridged, a conservative procedure was chosen. Thus, segmental resection of the ureter and primary end-to-end closure of the ureter was performed in 5 patients and ureteroneocystostomy in 3 patients. In nine patients local tumour excision was not feasible and nephroureterectomy was done. The survival rate at 3 and 10 years after ureteral resection as well as after nephroureterectomy was the same, 66% and 16%, respectively. Local excision of non-invasive low-grade ureteral tumours could be safely performed in selected patients, based on local findings and frozen section at the time of surgery.
对20例输尿管移行细胞肿瘤(TCUT)患者进行了回顾性研究。17例患者进行了肿瘤的手术探查。对术中冰冻切片活检进行评估,以决定手术干预的范围。如果能够进行肿瘤的根治性切除,并且输尿管缺损能够修复,则选择保守手术。因此,5例患者进行了输尿管节段性切除及输尿管端端原位吻合术,3例患者进行了输尿管膀胱再植术。9例患者因局部肿瘤切除不可行而进行了肾输尿管切除术。输尿管切除术后3年和10年的生存率以及肾输尿管切除术后的生存率相同,分别为66%和16%。基于手术时的局部情况及冰冻切片检查结果,对于部分经过选择的患者,可安全地进行非侵袭性低级别输尿管肿瘤的局部切除。