Michels J J, Peny J, Peny A M, Droz J P
Laboratoire d'Anatomie Pathologique, Centre François Baclesse, Caen, France.
Arch Anat Cytol Pathol. 1997;45(4):230-3.
One case of neuroblastoma arising in an adult immature testicular teratoma is described, with multiple systemic metastases, a partial response to intensive chemotherapy and a swift recurrence leading to death. Such instances of prevailing neuroblastoma with systemic metastases, have only seldomly been reported hitherto. Because of the teratoma and the focal presence of intratubular germ cell neoplasia of unclassified type, we think this tumor must be indeed of germ cell derivation.
本文描述了一例发生于成人未成熟睾丸畸胎瘤的神经母细胞瘤,伴有多处全身转移,对强化化疗有部分反应,但迅速复发并导致死亡。这种伴有全身转移的优势神经母细胞瘤病例,迄今报道甚少。鉴于畸胎瘤以及未分类的管内生殖细胞肿瘤的局灶性存在,我们认为该肿瘤确实起源于生殖细胞。