Abdul-Karim R W, Harris J E, Beydoun S N, Cuenca V G
Obstet Gynecol. 1976 Aug;48(2):239-41.
The effect of noncreatinine chromogens on the endogenous creatinine clearance (ECC) during pregnancy was investigated. It was found that these chromogens measured as plasma "creatinine" cause a significant reduction in the ECC value. This fact should be considered when the ECC value is used to evaluate renal function during pregnancy.