Miller M D, Wolfson L, Frank E, Cornes C, Silberman R, Ehrenpreis L, Zaltman J, Malloy J, Reynolds C F
Department of Psychiatry, University of Pittsburgh Medical Center, Pennsylvania, USA.
J Psychother Pract Res. 1997 Winter;7(1):47-55.
One hundred eighty subjects at least 60 years of age with recurrent unipolar major depression were recruited to participate in a depression treatment protocol. All patients received drug therapy with nortriptyline (NT) and interpersonal psychotherapy (IPT) with an experienced clinician. Acutely, 81% of subjects showed a full response to combined treatment. In the initial 127 subjects, the most common problem areas in therapy were role transition (41%), interpersonal disputes (34.5%), and grief (23%). Case vignettes are presented and discussed. The combination of IPT and NT showed a powerful antidepressant effect. IPT was readily adaptable to the needs of depressed elders.
招募了180名至少60岁的复发性单相重度抑郁症患者参与一项抑郁症治疗方案。所有患者均接受了去甲替林（NT）药物治疗以及由经验丰富的临床医生进行的人际心理治疗（IPT）。急性发作期，81%的患者对联合治疗表现出完全缓解。在最初的127名患者中，治疗中最常见的问题领域是角色转变（41%）、人际纠纷（34.5%）和悲伤（23%）。文中呈现并讨论了病例 vignettes。IPT和NT的联合显示出强大的抗抑郁效果。IPT很容易适应老年抑郁症患者的需求。
