Kosmal A, Malinowska M, Kowalska D M
Department of Neurophysiology, Nencki Institute of Experimental Biology, Warsaw, Poland.
Acta Neurobiol Exp (Wars). 1997;57(3):165-88. doi: 10.55782/ane-1997-1224.
Thalamic and amygdaloid connections of three association auditory areas (AA1, AA2, AA3) of the superior temporal gyrus (STG) were investigated. In order to define the projections of the particular areas, injections of fluorescent tracers were made in three monkeys. Distribution of labeling indicates that area AA1 differs from areas AA2 and AA3 in patterns of both thalamo-cortical and amygdalo-cortical connections. Area AA1 receives its predominant inputs from the ventral and dorsal nuclei of the medical geniculate body (MGB). The amygdaloid projection to the area AA1 originates from the basal nuclei, whereas input from the lateral nucleus was not found. The characteristic thalamic projections to areas AA2 and AA3 originate from the dorsal MGB nucleus and the polymodal nuclei of the posterior thalamus. The density of projections from the dorsal nucleus gradually decreases from area AA1 to area AA3 while projections from the Plm, Sg and Lim nuclei increase in the same direction. Areas AA2 and AA3 are the source of strong connections with the lateral nucleus of amygdala, which density increases progressively when injections shift from area AA2 to AA3. The basal and accessory basal nuclei are the source of a less significant amygdalofugal projections to both cortical areas. Thus, our experimental data indicate that influence of the polymodal thalamic nuclei increases substantially in the direction of the higher order association areas. The strong relation of the same cortical areas with the lateral amygdaloid nucleus might suggest that areas AA2 and AA3, in addition to auditory input are the site of transfer of complex sensory information to the amygdala.
研究了颞上回（STG）三个联合听觉区域（AA1、AA2、AA3）的丘脑和杏仁核连接。为了确定特定区域的投射，对三只猴子进行了荧光示踪剂注射。标记分布表明，AA1区域在丘脑皮质和杏仁核皮质连接模式上与AA2和AA3区域不同。AA1区域主要从内侧膝状体（MGB）的腹侧和背侧核接收输入。杏仁核对AA1区域的投射起源于基底核，而未发现来自外侧核的输入。对AA2和AA3区域的特征性丘脑投射起源于背侧MGB核和丘脑后部的多模态核。从背侧核的投射密度从AA1区域到AA3区域逐渐降低，而从Plm、Sg和Lim核的投射在相同方向上增加。AA2和AA3区域是与杏仁核外侧核有强连接的来源，当注射从AA2区域转移到AA3区域时，其密度逐渐增加。基底核和副基底核是对两个皮质区域杏仁核传出投射不太显著的来源。因此，我们的实验数据表明，多模态丘脑核的影响在向高阶联合区域的方向上显著增加。相同皮质区域与杏仁核外侧核的强关系可能表明，AA2和AA3区域除了听觉输入外，还是复杂感觉信息向杏仁核传递的部位。
