Darvas K, Molnár Z, Irtó I, Tarjányi M, Flautner L
1st Surgical Department, Semmelweis University Medical School, Budapest, Hungary.
Acta Chir Hung. 1997;36(1-4):72-5.
Spreading of laparoscopic techniques caused changes in anaesthesiological contraindications. In the first period laparoscopy was contraindicated in ischemic heart disease (IHD). Early mobilisation and short postoperative period are positive goals, IHD was taken out of contraindications. Present study compares changes in circulatory, blood gas and acid-base balance values during laparoscopic cholecystectomy (LC) in groups of patients ASA I-II. and ASA III. with IHD. There were 30 patients in group ASA I-II, 30 patients with IHD in category of ASA III. investigated during LC. Fifteen patients of both groups went under Propofol-Fentanyl (TIVA) anaesthesia, others were on Propofol-Fentanyl-N2O (IVA) protocol. All of them got also Atracurium. Pulse rate, mean arterial pressure, O2 saturation and end tidal CO2, blood gases and acid-base state were recorded before induction, after CO2 insufflation, after desufflation, 1 and 3 hours postoperatively. After CO2 insufflation there was a moderate tachycardia in both ASA III. groups (74/min-->88/min). In all groups pCO2 increased (40-->48 mmHg) but normalised till the 3rd postoperative hours (42 mmHg). Ventricular extrasystoles appeared in 3 ASA III. patients in IVA group. Three high risk patients had serious metabolic acidosis postoperatively. Present time the ischaemic heart disease does not contraindicates laparoscopic interventions. TIVA with Propofol is better choice because of its favourable effects on circulation and acid-base balance. Using N2O caused higher grade of intestinal distension. The cardio-respiratory, blood gas parameters and acid-base balance have to be monitorised in perioperative period of laparoscopic surgery.
腹腔镜技术的推广导致了麻醉禁忌证的变化。在第一阶段,缺血性心脏病(IHD)患者禁忌进行腹腔镜手术。早期活动和短的术后恢复时间是积极目标,IHD已不再属于禁忌证。本研究比较了ASA I-II级和ASA III级合并IHD的患者在腹腔镜胆囊切除术(LC)期间循环、血气和酸碱平衡值的变化。ASA I-II级组有30例患者,ASA III级合并IHD组有30例患者在LC期间接受研究。两组各有15例患者接受丙泊酚-芬太尼(全凭静脉麻醉)麻醉,其他患者采用丙泊酚-芬太尼-N₂O(静脉吸入复合麻醉)方案。所有患者均使用阿曲库铵。在诱导前、二氧化碳气腹后、气腹解除后、术后1小时和3小时记录心率、平均动脉压、血氧饱和度和呼气末二氧化碳分压、血气及酸碱状态。二氧化碳气腹后,两个ASA III级组均出现中度心动过速(74次/分钟→88次/分钟)。所有组的pCO₂均升高(40→48 mmHg),但在术后第3小时恢复正常(42 mmHg)。静脉吸入复合麻醉组的3例ASA III级患者出现室性早搏。3例高危患者术后出现严重代谢性酸中毒。目前,缺血性心脏病并不禁忌腹腔镜手术。丙泊酚全凭静脉麻醉是更好的选择,因为它对循环和酸碱平衡有有利影响。使用N₂O会导致更高程度的肠胀气。在腹腔镜手术围手术期必须监测心肺、血气参数和酸碱平衡。