Galetta S L, Balcer L J, Lieberman A P, Syed N A, Lee J M, Oberholtzer J C
Department of Neurology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
Neurology. 1997 Dec;49(6):1720-3. doi: 10.1212/wnl.49.6.1720.
We report an elderly patient with aggressive steroid-refractory giant cell arteritis manifesting as myelopathy and bilateral visual loss while on treatment. Pathologically, spinal cord infarction was observed and was due to extensive necrotizing granulomatous arteritis of spinal arteries. Spinal cord damage in giant cell arteritis is rare. One prior autopsy report of spinal cord infarction in giant cell arteritis did not identify vasculitic changes in the spinal arteries.
我们报告了一例老年患者,患有侵袭性类固醇难治性巨细胞动脉炎,在治疗期间表现为脊髓病和双眼视力丧失。病理检查发现脊髓梗死,原因是脊髓动脉广泛坏死性肉芽肿性动脉炎。巨细胞动脉炎导致的脊髓损伤很罕见。之前一份关于巨细胞动脉炎脊髓梗死的尸检报告未发现脊髓动脉的血管炎改变。