• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Heterogeneity of sickle cell anaemia in Arabs: review of cases with various amounts of fetal haemoglobin.阿拉伯人中镰状细胞贫血的异质性：对不同胎儿血红蛋白含量病例的综述。
J Med Genet. 1979 Dec;16(6):428-30. doi: 10.1136/jmg.16.6.428.
2
Red cell genetic abnormalities in Peninsular Arabs: sickle haemoglobin, G6PD deficiency, and alpha and beta thalassaemia.半岛阿拉伯人的红细胞遗传异常：镰状血红蛋白、葡萄糖-6-磷酸脱氢酶缺乏症以及α和β地中海贫血。
J Med Genet. 1986 Jun;23(3):245-51. doi: 10.1136/jmg.23.3.245.
3
Blood groups and types, hemoglobin variants, and G-6-PD deficiency among Abu Dhabians in the United Arab Emirates.
Am J Phys Anthropol. 1980 May;52(4):481-4. doi: 10.1002/ajpa.1330520404.
4
Heterogeneity and variation of clinical and haematological expression of haemoglobin S in Saudi Arabs.沙特阿拉伯人中血红蛋白S临床和血液学表现的异质性与变异性。
Acta Haematol. 1992;88(2-3):67-71. doi: 10.1159/000204654.
5
Fetal haemoglobin production and the sickle gene in the oases of Eastern Saudi Arabia.
Br J Haematol. 1978 Nov;40(3):415-29. doi: 10.1111/j.1365-2141.1978.tb05813.x.
6
Improved diagnosis of sickle cell mutation by a robust amplification refractory polymerase chain reaction.
Clin Biochem. 1999 Nov;32(8):677-80. doi: 10.1016/s0009-9120(99)00071-5.
7
The population dynamics of hemoglobins A, A, F and S in the context of the hemoglobinopathies HbS and α-thalassemia in Kenyan infants.肯尼亚婴儿中镰状血红蛋白病（HbS）和α地中海贫血背景下血红蛋白A、A2、F和S的群体动态。
Haematologica. 2019 May;104(5):e184-e186. doi: 10.3324/haematol.2018.199596. Epub 2018 Nov 22.
8
Sickle cell-beta 0-thalassaemia in Saudi Arabia.沙特阿拉伯的镰状细胞-β0-地中海贫血
Hum Hered. 1987;37(4):211-6. doi: 10.1159/000153705.
9
A benign sickle-cell disease in a Saudi subject with beta zero-thalassemia and glucose-6-phosphate dehydrogenase deficiency.一名患有β0地中海贫血和葡萄糖-6-磷酸脱氢酶缺乏症的沙特患者的良性镰状细胞病。
Hum Hered. 1989;39(2):118-20. doi: 10.1159/000153847.
10
Interaction between glucose-6-phosphate dehydrogenase deficiency and sickle cell gene in Saudi Arabia.沙特阿拉伯葡萄糖-6-磷酸脱氢酶缺乏症与镰状细胞基因之间的相互作用。
Trop Geogr Med. 1987 Jan;39(1):32-5.

引用本文的文献

1
Epidemiological and molecular study of hemoglobinopathies in Mauritanian patients.毛里塔尼亚患者血红蛋白病的流行病学和分子研究。
Mol Genet Genomic Med. 2022 Oct;10(10):e2048. doi: 10.1002/mgg3.2048. Epub 2022 Sep 15.
2
Y-chromosome R-M343 African lineages and sickle cell disease reveal structured assimilation in Lebanon.Y 染色体 R-M343 非洲谱系和镰状细胞病揭示了黎巴嫩的结构化同化。
J Hum Genet. 2011 Jan;56(1):29-33. doi: 10.1038/jhg.2010.131. Epub 2010 Oct 28.

本文引用的文献

1
Studies on abnormal hemoglobins. I. Their demonstration in sickle cell anemia and other hematologic disorders by means of alkali denaturation.异常血红蛋白的研究。I. 通过碱变性法在镰状细胞贫血和其他血液系统疾病中的显示
Blood. 1951 May;6(5):413-28.
2
A series of new screening procedures for pyruvate kinase deficiency, glucose-6-phosphate dehydrogenase deficiency, and glutathione reductase deficiency.一系列针对丙酮酸激酶缺乏症、葡萄糖-6-磷酸脱氢酶缺乏症和谷胱甘肽还原酶缺乏症的新筛查程序。
Blood. 1966 Oct;28(4):553-62.
3
Rapid electrophoresis and quantitation of haemoglobins on cellulose acetate.醋酸纤维素上血红蛋白的快速电泳及定量分析
J Clin Pathol. 1965 Nov;18(6):790-2. doi: 10.1136/jcp.18.6.790.
4
Benign sickle-cell anaemia.
Lancet. 1972 Dec 2;2(7788):1163-7. doi: 10.1016/s0140-6736(72)92592-5.
5
Haemoglobin Bart's in Saudi Arabia.沙特阿拉伯的血红蛋白巴特氏症
Br J Haematol. 1975 Feb;29(2):221-34. doi: 10.1111/j.1365-2141.1975.tb01816.x.
6
Fetal haemoglobin production and the sickle gene in the oases of Eastern Saudi Arabia.
Br J Haematol. 1978 Nov;40(3):415-29. doi: 10.1111/j.1365-2141.1978.tb05813.x.
7
Natural history of sickle cell anemia in Saudi Arabs. A study of 270 subjects.沙特阿拉伯人镰状细胞贫血的自然病史。对270名受试者的研究。
Ann Intern Med. 1978 Jan;88(1):1-6. doi: 10.7326/0003-4819-88-1-1.

阿拉伯人中镰状细胞贫血的异质性：对不同胎儿血红蛋白含量病例的综述。

Heterogeneity of sickle cell anaemia in Arabs: review of cases with various amounts of fetal haemoglobin.

作者信息

Kamel K

出版信息

J Med Genet. 1979 Dec;16(6):428-30. doi: 10.1136/jmg.16.6.428.

DOI:10.1136/jmg.16.6.428
PMID:94097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1012587/
Abstract

A study is presented on eleven patients with homozygous sickle cell anaemia. They are non-Sheeah Arabs from the United Arab Emirates on the south-eastern coast of the Arabian Peninsula. The proportions of fetal haemoglobin in these patients are variable, and there is a marked variation in the severity of their disease condition; these facts are not related. African sickle cell gene admixture is a likely affecting factor.

摘要

本文介绍了一项针对11例纯合子镰状细胞贫血患者的研究。他们是来自阿拉伯半岛东南海岸阿拉伯联合酋长国的非希贾兹阿拉伯人。这些患者中胎儿血红蛋白的比例各不相同，并且他们疾病状况的严重程度存在显著差异；这些事实并无关联。非洲镰状细胞基因混合可能是一个影响因素。