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[重症患者术后感染]

[Postoperative infections in critically ill patients].

作者信息

Palomar M, Serra J

机构信息

Servicio de Medicina Intensiva, Hospital General Universitari Vall d'Hebron, Barcelona.

出版信息

Enferm Infecc Microbiol Clin. 1997 Oct;15 Suppl 3:20-6.

PMID:9410079
Abstract

Patients subjected to surgery often develop nosocomial infections, among which the intra-abdominal ones stand out as being a common cause of septicemia, multi-organ failure, and death of the critical patients. Advances have been made in the study of the physiopathology by studying the mediators which are responsible for the systemic inflammatory response, the microbiology (changes in the pathogen type and in the antimicrobial sensitivity), and for the clinical picture (cholecystitis, tertiary peritonitis). Abdominal ultra-sound and computerized axial tomography have contributed greatly to the diagnosis of these infections. The new treatment techniques are discussed, both of the drainage of the septic focus (percutaneous or surgical), as of the antimicrobial treatment and the supportive measures. The diagnostic and therapeutic advances have modified the prognosis of these patients, although this continues to be poor when there is development of the multi-organ failure syndrome.

摘要

接受手术的患者常常会发生医院感染,其中腹腔内感染尤为突出,是导致败血症、多器官功能衰竭以及危重症患者死亡的常见原因。通过研究引发全身炎症反应的介质、微生物学(病原体类型及抗菌敏感性的变化)以及临床表现(胆囊炎、三期腹膜炎),在生理病理学研究方面取得了进展。腹部超声和计算机断层扫描对这些感染的诊断有很大帮助。文中讨论了新的治疗技术,包括感染灶引流(经皮或手术引流)、抗菌治疗以及支持措施。尽管当多器官功能衰竭综合征发生时患者预后仍然很差,但诊断和治疗方面的进展已经改变了这些患者的预后。

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