Albåge A, Bengtsson L, Van Der Linden J, Lindblom D, Kennebäck G, Flodin T, Nygren A, Svedenhag J
Thoraxkliniken, Samtliga vid HjärtLungKärl-divisionen, Huddinge sjukhus.
Lakartidningen. 1997 Oct 1;94(40):3511-5.
Atrial fibrillation (AF) is a common arrhythmia associated with significant morbidity and increased mortality, partly due to the increased risk of stroke. The maze procedure, introduced by James Cox of the USA, is an internationally established surgical alternative in cases of unsuccessful medical or catheterised treatment of paroxysmal or chronic AF. It is an open heart procedure, involving multiple transmural incisions and continuous suture lines in both atria. By creating a maze of atrial tissue, the re-entrant circuits causing the AF are interrupted, hence re-establishing regular sinus rhythm and atrioventricular synchronization. The article reviews the initial 3-year experience of the procedure in 10 patients with AF, either paroxysmal (n = 5) or chronic (n = 5). The indications for surgery were disabling symptoms in all 10 cases, medical treatment failure in nine cases, previous AF-associated stroke in three cases, and a significant atrial septal defect in one case. All patients underwent extensive investigation both pre- and post-operatively. Postoperatively, nine of the 10 patients manifested regular sinus or atrial rhythm and freedom from or amelioration of preoperative symptoms associated with AF. There were no deaths, neurological complications or long-term recurrence of arrhythmia. One patient had an early recurrence of AF that was not amenable to medical treatment, and was subsequently treated with His' bundle ablation. Of the remaining nine patients, seven manifested signs of some postoperative atrial contraction at echocardiography, the occurrence of which needs to be borne in mind with a view to reducing the risk of future thromboembolic events. We recommend the maze procedure as an attractive surgical option in cases of unsuccessful medical treatment of paroxysmal or chronic AF.
心房颤动(AF)是一种常见的心律失常,与显著的发病率和死亡率增加相关,部分原因是中风风险增加。美国的詹姆斯·考克斯引入的迷宫手术,是阵发性或慢性房颤药物治疗或导管治疗失败时国际公认的手术替代方案。这是一种心脏直视手术,涉及在两个心房进行多个透壁切口和连续缝合线。通过创建心房组织迷宫,导致房颤的折返环路被中断,从而重新建立规则的窦性心律和房室同步。本文回顾了该手术在10例房颤患者(阵发性5例,慢性5例)中的最初3年经验。手术指征在所有10例中均为致残症状,9例药物治疗失败,3例既往有房颤相关中风,1例有明显房间隔缺损。所有患者在术前和术后均接受了广泛检查。术后,10例患者中有9例表现出规则的窦性或心房节律,术前与房颤相关的症状消失或改善。无死亡、神经并发症或心律失常长期复发。1例患者房颤早期复发,药物治疗无效,随后接受希氏束消融治疗。在其余9例患者中,7例在超声心动图检查中表现出术后心房收缩的迹象,考虑到降低未来血栓栓塞事件的风险,需要牢记这一情况的发生。我们推荐迷宫手术作为阵发性或慢性房颤药物治疗失败时一种有吸引力的手术选择。