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[Study of the Leiden mutation (factor VQ 506), the most frequent cause of thrombophilia, in 116 thrombosis patients].

作者信息

Nagy A, Melegh B, Losonczy H

机构信息

Pécsi Orvostudományi Egyetem I. sz. Belgyógyászati Klinika.

出版信息

Orv Hetil. 1997 Nov 2;138(44):2797-800.

PMID:9411348
Abstract

The incidence of Leiden mutation was examined by PCR method in 116 thrombophilic patients in random fashion. Mean age at the first thrombotic episode was 30.97 years. 90 patients had positive family history for thrombosis, 67 had more than one thrombotic episodes. APC resistance with laboratory test was found in 51 cases (44%). F V Leiden mutation was proven in 44 patients (38%). 10 being homozygous and 34 heterozygous out of them.

摘要

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引用本文的文献

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Epidemiology of activated protein C resistance and factor v leiden mutation in the mediterranean region.地中海地区活化蛋白 C 抵抗和因子 V 莱顿突变的流行病学。
Mediterr J Hematol Infect Dis. 2011;3(1):e2011037. doi: 10.4084/MJHID.2011.037. Epub 2011 Sep 8.