Thiel A
Klinik für Medizinische Psychologie und Psychotherapie, Universität Innsbruck.
Psychother Psychosom Med Psychol. 1997 Sep-Oct;47(9-10):332-45.
This review summarises the results of psychopharmacological treatment studies on anorexia and, bulimia nervosa. Although several drugs have tested in patients with anorexia nervosa, the outcome of controlled studies has been disappointing. Trials of pharmacotherapy for bulimia nervosa have demonstrated that tricyclic antidepressants, monoamine oxidase inhibitors and selective serotonin reuptake inhibitors significantly reduce the frequency of binge eating and purging. In some cases, psychotherapists should accept the necessity of psychopharmacological intervention, although this does not imply a known biological cause of the eating disorder. However, the significance of antidepressant medication in the overall treatment of anorexia and bulimia nervosa remains unclear.
本综述总结了关于神经性厌食症和神经性贪食症的心理药物治疗研究结果。尽管已有多种药物在神经性厌食症患者中进行了测试，但对照研究的结果并不理想。针对神经性贪食症的药物治疗试验表明，三环类抗抑郁药、单胺氧化酶抑制剂和选择性5-羟色胺再摄取抑制剂可显著降低暴饮暴食和催吐的频率。在某些情况下，心理治疗师应认识到心理药物干预的必要性，尽管这并不意味着饮食失调存在已知的生物学病因。然而，抗抑郁药物在神经性厌食症和神经性贪食症整体治疗中的意义仍不明确。
