Hossain A M, Kirk D N, Mitra G
Steroids. 1976 May;27(5):603-8. doi: 10.1016/s0039-128x(76)90096-9.
The first convenient chemical synthesis of 7alpha-hydroxyandrost-4-ene-3,17-dione is reported. Androsta-4,6-diene3, 17-dione was converted into its 6alpha, 7alpha-epoxy-derivative; reduction of the epoxide with aluminum amalgam gave 7alpha-hydroxyandrost-4-ene-3,17-dione. This reducing agent is more efficient than chromous acetate for the purpose.
首次报道了7α-羟基雄甾-4-烯-3,17-二酮的简便化学合成方法。雄甾-4,6-二烯-3,17-二酮被转化为其6α,7α-环氧衍生物；用铝汞齐还原环氧化物得到7α-羟基雄甾-4-烯-3,17-二酮。在此用途上，这种还原剂比醋酸亚铬更有效。
