Piven J, Palmer P
University of Iowa College of Medicine, Iowa City, USA.
J Child Psychol Psychiatry. 1997 Nov;38(8):1011-21. doi: 10.1111/j.1469-7610.1997.tb01618.x.
This study compares parents of two autistic children with parents of a Down syndrome (DS) proband, on tests of intelligence, reading and spelling, and executive function. Autism parents performed significantly worse than DS parents on performance IQ, a test of executive function, and some reading measures (e.g. passage comprehension and rapid automatized naming). These results suggest that cognitive deficits may be an expression of the underlying genetic liability for autism and that these characteristics may contribute to a more broadly defined autism phenotype.
本研究比较了两名自闭症儿童的父母与一名唐氏综合征（DS）先证者的父母在智力、阅读与拼写以及执行功能测试方面的表现。自闭症儿童的父母在操作智商、一项执行功能测试以及一些阅读指标（如篇章理解和快速自动命名）上的表现显著差于唐氏综合征儿童的父母。这些结果表明，认知缺陷可能是自闭症潜在遗传易感性的一种表现，并且这些特征可能促成了一个更广义定义的自闭症表型。
