Teichmann W, Vogel H C, Schäbitz J, Schmeisser M, Lukesch K H
Z Gesamte Inn Med. 1976 Mar 15;31(6):161-6.
During 6 months lidoflazine was applied ambulatorily in a dosage of 240 mg/a day orally in 21 patients after finished infarction. After 2 to 3 weeks one patient each was excluded due to incompatibility or reinfarction, respectively. In the remaining 19 patients consumption of nitrangin, mechanocardiogram, ECG and blood pressure were controlled in regular intervals during and after ergometric load as well as clinico-chemical examinations performed. The consumption of nitrangin clearly decreased in the course of the time of observation. The tolerance ofthe medicament was good. At the end of the treatment the unchanging load was tolerated with lower pulse rate, slightly decreased blood pressure and shortened period of isometric contraciton and period of the increase of blood pressure. The present results were discussed compared with literature.
在6个月期间，对21例心肌梗死后患者采用利多氟嗪进行门诊治疗，口服剂量为每日240mg。2至3周后，分别有1例患者因不耐受或再次梗死被排除。对其余19例患者，在运动负荷期间和之后定期监测硝酸甘油用量、机械心动图、心电图和血压，并进行临床化学检查。在观察期间，硝酸甘油用量明显减少。药物耐受性良好。治疗结束时，在相同负荷下，患者心率降低，血压略有下降，等长收缩期和血压上升期缩短。将目前的结果与文献进行了讨论。
