Goffeng A R, Milsom I, Lindstedt G, Lundberg P A, Andersch B
Department of Obstetrics and Gynecology, Sahlgrens University Hospital, University of Göteborg, Sweden.
Gynecol Obstet Invest. 1997;44(4):224-8. doi: 10.1159/000291533.
The aim of this study was to determine fetal fibronectin in vaginal fluid of women in prolonged pregnancy, its relationship to a modified Bishop score and its predictiveness of delivery within 3 days. Vaginal samples were collected from 80 women at 42 weeks of gestation for the fetal fibronectin assay. A modified Bishop score was estimated. Fetal fibronectin was determined by a quantitative enzyme immunoassay. The concentration of fetal fibronectin in vaginal fluid was elevated in only 36 of the 80 women. The Bishop score and the time between sampling and delivery were not associated with an elevated fetal fibronectin (> or = 0.05 mg/l). We conclude that fetal fibronectin is not a good indicator of delivery within 3 days. The findings add to our understanding of the complexity of the etiology of postterm labor.
本研究旨在测定过期妊娠妇女阴道液中的胎儿纤连蛋白，探讨其与改良Bishop评分的关系及其对3天内分娩的预测价值。在妊娠42周时，从80名妇女中采集阴道样本进行胎儿纤连蛋白检测，并评估改良Bishop评分。采用定量酶免疫法测定胎儿纤连蛋白。80名妇女中仅36名阴道液中胎儿纤连蛋白浓度升高。Bishop评分以及采样至分娩的时间与胎儿纤连蛋白升高（≥0.05 mg/l）无关。我们得出结论，胎儿纤连蛋白并非3天内分娩的良好指标。这些发现加深了我们对过期产病因复杂性的理解。
