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[葡萄糖对文昌鱼肠道上皮细胞的影响]

[The effect of glucose on the intestinal epithelial cells of the lancet Branchiostoma lanceolatum].

作者信息

Poliakova T I, Plisetskaia E M

出版信息

Zh Evol Biokhim Fiziol. 1976 Mar-Apr;12(2):184-7.

PMID:941573
Abstract

Animals were kept for 24 hours at 3-5 degrees C in sea water to which 100 mg% of glucose was added. Control animals were kept in the sea water without glucose. In gut epithelium of the lancelot 3 types of cells were revealed which correspond to those described earlier, viz. "digestive", "zymogen" and fine granular ones. Cytoplasm of the cells of the III type contains numerous granules of paraldehydefuchsine-positive material. After glucose loading, degranulation of the cytoplasm in these cells is more intensive than in cells of two other types. The product is released into the gut. The possibility of production of insulin or insulin-like substance by the cells of the III type is discussed.

摘要

将动物置于添加了100mg%葡萄糖的海水中,在3 - 5摄氏度下饲养24小时。对照动物饲养在不含葡萄糖的海水中。在文昌鱼的肠上皮中发现了3种类型的细胞,与先前描述的细胞相对应,即“消化”细胞、“酶原”细胞和细颗粒细胞。III型细胞的细胞质含有大量副醛品红阳性物质颗粒。葡萄糖负荷后,这些细胞细胞质的脱粒比其他两种类型的细胞更强烈。产物释放到肠道中。讨论了III型细胞产生胰岛素或胰岛素样物质的可能性。

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