Przybylski J, Trzebski A
Acta Physiol Pol. 1976 May-Jun;27(3):205-14.
Bilateral electrolytic lesions of the solitary tract nucleus in control Wistar albino rats as well as in Okamoto rats with spontaneous arterial hypertension caused a considerable rise in the arterial blood pressure. Quantitative comparison of blood pressure rise in normotensive and hypertensive rats demonstrated that the rise in the systolic and mean blood pressure was not significantly different in both groups of animals. However, the rats with spontaneous hypertension reacted, with a greater rise in the diastolic pressure. A characteristic feature observed in the normotensive rats was a high rise in pulse pressure following lesion of the solitary tract nucleus while in the rats with spontaneous hypertension this change was not found. The authors conclude that increased peripheral vascular resistance in the rats with spontaneous hypertension is not due to inhibition or resetting of the baroreceptor reflex.
对正常的Wistar白化大鼠以及患有自发性动脉高血压的冈本大鼠的孤束核进行双侧电解损伤，导致动脉血压显著升高。对正常血压和高血压大鼠血压升高情况的定量比较表明，两组动物的收缩压和平均血压升高没有显著差异。然而，患有自发性高血压的大鼠反应更为明显，舒张压升高幅度更大。在正常血压大鼠中观察到的一个特征是，孤束核损伤后脉压大幅升高，而在患有自发性高血压的大鼠中未发现这种变化。作者得出结论，患有自发性高血压的大鼠外周血管阻力增加并非由于压力感受器反射的抑制或重置。
