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[常染色体显性多囊肾。附2例报告并文献复习]

[Autosomal dominant polycystic kidney. Apropos of 2 cases. Review of the literature].

作者信息

Tsatsaris V, Rondeau E, Salat-Baroux J, Uzan S

机构信息

Service de Gynécologie et Obstétrique, Hôpital Tenon, Paris.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1997;26(5):529-32.

PMID:9417467
Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disease. Genetic molecular methods can make the diagnosis of at least three different types of ADPKD. ADPKD concerns young people and complications such as hypertension and decreased renal function occur more frequently if onset is early, if it is a type 1, and if the patient is a woman. The pregnant woman with autosomal dominant cystic disease is at particular high risk of obstetrical complications. Prenatal diagnosis is possible.

摘要

常染色体显性多囊肾病(ADPKD)是最常见的遗传性疾病。基因分子方法能够诊断至少三种不同类型的ADPKD。ADPKD多见于年轻人,若发病早、为1型且患者为女性,则高血压和肾功能减退等并发症更常出现。患有常染色体显性囊性疾病的孕妇发生产科并发症的风险特别高。产前诊断是可行的。

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