胰岛素在酪氨酸和色氨酸从血液转运至大脑过程中的可能作用。
Possible role of insulin in the transport of tyrosine and tryptophan from blood to brain.
作者信息
Tagliamonte A, DeMontis M G, Olianas M, Onali P L, Gessa G L
出版信息
Adv Exp Med Biol. 1976;69:89-94. doi: 10.1007/978-1-4684-3264-0_7.
PMID:941747
Abstract
The administration of insulin or the ingestion of glucose increases the concentration of tryptophan and tyrosine in the brain. This increase is associated with a parallel decrease in the concentration of free tryptophan and tyrosine in serum. The results suggest that insulin enhances the transport of tyrosine and tryptophan from blood to brain. The results, moreover, suggest that exogenous or endogenous insulin enhances the transport of tyrosine and tryptophan from blood to brain.
摘要
注射胰岛素或摄入葡萄糖会增加大脑中色氨酸和酪氨酸的浓度。这种增加与血清中游离色氨酸和酪氨酸浓度的相应降低有关。结果表明，胰岛素可增强酪氨酸和色氨酸从血液到大脑的转运。此外，结果还表明，外源性或内源性胰岛素均可增强酪氨酸和色氨酸从血液到大脑的转运。
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