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[Hematopoietic stem cell transplantations in treatment of autoimmune diseases].

作者信息

Gratwohl A, Tyndall A

机构信息

Department Innere Medizin Kantonsspital, Basel, Switzerland.

出版信息

Z Rheumatol. 1997 Jul-Aug;56(4):173-7. doi: 10.1007/s003930050032.

DOI:10.1007/s003930050032
PMID:9417757
Abstract

Autologous and allogeneic blood or marrow transplants are currently under intensive discussion as therapeutic option for patients with severe autoimmune disorders. Preclinical data as well as case reports from patients with transplants for other indications and concommitant autoimmune disorders support such concepts. In order to advance in a coordinated way the European League against Rheumatism EULAR and the European Group for Blood and Marrow Transplantation EBMT prepared common guide lines on how to proceed. They are presented and summarised. Clear clinical data are still missing. Preliminary data are promising and protocols for prospective studies are being prepared. They should allow a better evaluation of the procedures in a few years from now.

摘要

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引用本文的文献

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Autologous haematopoietic stem cell transplantation (AHSCT) in autoimmune disease adult patients in France: analysis of the long-term outcome from the French Society for Bone Marrow Transplantation and Cellular Therapy (SFGM-TC).法国自体造血干细胞移植(AHSCT)治疗成人自身免疫性疾病患者:法国骨髓移植和细胞治疗学会(SFGM-TC)的长期结果分析。
Clin Rheumatol. 2019 May;38(5):1501-1511. doi: 10.1007/s10067-019-04435-2. Epub 2019 Jan 21.
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Stem cell therapy in autoimmune rheumatic diseases: a comprehensive review.干细胞治疗自身免疫性风湿病:全面综述。
Clin Rev Allergy Immunol. 2014 Oct;47(2):244-57. doi: 10.1007/s12016-014-8445-8.
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Does hemopoietic stem cell transplantation have a role in treatment of severe rheumatoid arthritis?
造血干细胞移植在重症类风湿关节炎的治疗中是否有作用?
J Clin Immunol. 2000 Jan;20(1):17-23. doi: 10.1023/a:1006634309251.