van Merkesteyn J P, Groot R H, van den Akker H P, Bakker D J, Borgmeijer-Hoelen A M
Department of Oral and Maxillofacial Surgery, Academic Hospital Leiden, The Netherlands.
Int J Oral Maxillofac Surg. 1997 Dec;26(6):450-4. doi: 10.1016/s0901-5027(97)80012-4.
Chronic suppurative osteomyelitis of the mandible is often considered difficult to treat and may lead to refractory osteomyelitis. Sixteen patients with chronic suppurative osteomyelitis of the mandible were treated with a relatively simple protocol, consisting of sequestrectomy or decortication and i.v. antimicrobial therapy for one week, followed by oral penicillin for three weeks. Only one case showed recurrence of symptoms, which was treated successfully in a second session. It is concluded that combined surgical and antimicrobial therapy should be sufficient to cure most cases of chronic suppurative osteomyelitis of the mandible.
下颌骨慢性化脓性骨髓炎通常被认为难以治疗，且可能导致难治性骨髓炎。16例下颌骨慢性化脓性骨髓炎患者采用了一种相对简单的治疗方案，包括死骨切除术或骨皮质剥除术以及静脉注射抗菌治疗一周，随后口服青霉素三周。仅1例出现症状复发，在第二次治疗中成功治愈。结论是，手术和抗菌联合治疗应足以治愈大多数下颌骨慢性化脓性骨髓炎病例。
