Cordier A C, Denef J F, Haumont S M
Am J Anat. 1976 Aug;146(4):339-57. doi: 10.1002/aja.1001460402.
The thyroid gland of Snell's dwarf mice consists of small follicles with flattened epithelium, partly differentiated cords and undifferentiated masses. Many adipocytes are found. The ultimobranchial cysts are well developed. Parafollicular cells are normal. In the partly organized cords, microfollicular cells are some small follicles limited by two or three cells are seen. The presence of these structures led us to think that they represent the first stages of normal folliculogenesis, described as the fusion of two adjacent unicellular microfollicles. Their further growth is the result of the coalescing of small adjacent follicles or of cellular multiplication. The presence of undifferentiated masses and partly differentiated cords, in dwarf mice, seems due to a developmental arrest rather than to aberrant development. This disorder of organogenesis is ascribed mainly to a lack of pituitary growth hormone.
斯内尔侏儒小鼠的甲状腺由上皮扁平的小滤泡、部分分化的索状结构和未分化的团块组成。发现许多脂肪细胞。鳃后囊肿发育良好。滤泡旁细胞正常。在部分组织化的索状结构中，可见由两三个细胞限制的一些小滤泡即微滤泡细胞。这些结构的存在使我们认为它们代表正常滤泡发生的最初阶段，被描述为两个相邻单细胞微滤泡的融合。它们的进一步生长是相邻小滤泡合并或细胞增殖的结果。在侏儒小鼠中未分化团块和部分分化索状结构的存在，似乎是由于发育停滞而非异常发育。这种器官发生紊乱主要归因于垂体生长激素缺乏。
