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边缘型人格障碍的药物治疗

Pharmacotherapy of borderline personality disorder.

作者信息

Hirschfeld R M

机构信息

Department of Psychiatry & Behavioral Sciences, University of Texas Medical Branch, Galveston 77555-0429, USA.

出版信息

J Clin Psychiatry. 1997;58 Suppl 14:48-52; discussion 53.

PMID:9418746
Abstract

Borderline personality disorder can be classified into four groups of symptoms: affective, impulsive, ego-interpersonal, and psychotic. Pharmacotherapy of borderline personality disorder should be directed at the severity of the symptoms in each of these groups, rather than by the presence or absence of the overall syndrome. This article reviews the pharmacotherapy of borderline personality disorder, with special emphasis on affective and impulsive symptoms. Overall, the MAOIs, the SSRIs, and the newer antidepressants (such as venlafaxine) provide the widest spectrum of effective treatment for the symptoms of borderline personality disorder.

摘要

边缘型人格障碍可分为四组症状

情感症状、冲动症状、自我人际症状和精神病性症状。边缘型人格障碍的药物治疗应针对这些组中每组症状的严重程度,而非依据整体综合征的有无。本文回顾了边缘型人格障碍的药物治疗,特别强调情感和冲动症状。总体而言,单胺氧化酶抑制剂、选择性5-羟色胺再摄取抑制剂及新型抗抑郁药(如文拉法辛)为边缘型人格障碍症状提供了最广泛有效的治疗。

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