儿童和青少年的斑贴试验：五年经验与随访
Patch testing in children and adolescents: five years' experience and follow-up.
作者信息
Shah M, Lewis F M, Gawkrodger D J
机构信息
Department of Dermatology, Royal Hallamshire Hospital, Sheffield, UK.
出版信息
J Am Acad Dermatol. 1997 Dec;37(6):964-8. doi: 10.1016/s0190-9622(97)70073-2.
BACKGROUND
Allergic contact dermatitis in children is a significant clinical problem. Little information is available concerning the value of patch testing and the outcome in these children.
OBJECTIVE
Our purpose was to assess the value of patch testing in children and the outcome of allergic contact dermatitis in childhood.
METHODS
Clinical data on 83 children patch tested during a 5-year period were assessed. Clinical follow-up on 68 subjects was performed.
RESULTS
Overall, 41 children had one or more allergic reactions (49%). Reactions to metals, topical preparations, and food additives were common. The clinical outcome at 6 months was significantly better for 36 children with a relevant allergen on patch testing than in 32 with no allergen or no relevant allergen (p = 0.006).
CONCLUSION
Patch testing is useful in the management of children suspected of having an allergic contact dermatitis. Patch testing and subsequent allergen avoidance may improve the prognosis in children with a relevant contact allergen.
背景
儿童过敏性接触性皮炎是一个重要的临床问题。关于斑贴试验在这些儿童中的价值及结果的信息较少。
目的
我们的目的是评估斑贴试验在儿童中的价值以及儿童过敏性接触性皮炎的结果。
方法
对5年期间接受斑贴试验的83名儿童的临床资料进行评估。对68名受试者进行了临床随访。
结果
总体而言，41名儿童有一次或多次过敏反应（49%）。对金属、外用制剂和食品添加剂的反应很常见。斑贴试验显示有相关变应原的36名儿童在6个月时的临床结果明显好于32名无变应原或无相关变应原的儿童（p = 0.006）。
结论
斑贴试验对疑似过敏性接触性皮炎的儿童的管理有用。斑贴试验及随后避免接触变应原可能改善有相关接触性变应原儿童的预后。
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