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丹麦儿童进行斑贴试验的过敏性接触性皮炎-全国多中心研究。

Allergic contact dermatitis in Danish children referred for patch testing - a nationwide multicentre study.

机构信息

Department of Dermatology and Venereology, Aarhus University Hospital, 8000, Aarhus C, Denmark.

出版信息

Contact Dermatitis. 2014 Feb;70(2):104-11. doi: 10.1111/cod.12129. Epub 2013 Sep 19.

DOI:10.1111/cod.12129
PMID:24102181
Abstract

BACKGROUND

Although contact allergy among children was previously considered to be rare, data from the past decade have shown that it is common among children and that the prevalence may be increasing.

OBJECTIVES

To describe the demographics of all children referred for patch testing in Denmark during 2003-2011, to examine the frequency and relevance of positive patch test reactions, and to assess the most common allergens.

METHODS

A retrospective analysis of the patch test data from the Danish National Database of Contact Allergy was performed.

RESULTS

Of 2594 children and adolescents aged 1-17 years, 25.1% had one or more positive patch test reactions. The associated relevance was 66.4%. The most common sensitizers were metals, fragrances, and hair dyes. The frequency of positive patch test reactions and allergic contact dermatitis was significantly higher among girls.

CONCLUSIONS

Allergic contact dermatitis in children is a significant clinical problem. Contact allergy should always be considered when children with recalcitrant eczema are encountered, and special attention should be paid to girls. Patch testing is important, and children may be tested with the same patch test concentrations as adults.

摘要

背景

尽管儿童接触过敏以前被认为很少见,但过去十年的数据表明,儿童接触过敏很常见,而且患病率可能在增加。

目的

描述 2003-2011 年期间丹麦所有因斑贴试验而转诊的儿童的人口统计学特征,检查阳性斑贴试验反应的频率和相关性,并评估最常见的过敏原。

方法

对丹麦国家接触过敏数据库的斑贴试验数据进行回顾性分析。

结果

在 2594 名 1-17 岁的儿童和青少年中,25.1%有一个或多个阳性斑贴试验反应。相关的相关性为 66.4%。最常见的致敏原是金属、香料和染发剂。女孩的阳性斑贴试验反应和过敏性接触性皮炎的频率明显更高。

结论

儿童过敏性接触性皮炎是一个重大的临床问题。当遇到顽固湿疹的儿童时,应始终考虑接触过敏,应特别关注女孩。斑贴试验很重要,儿童可以用与成人相同的斑贴试验浓度进行测试。

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