通过双能X线吸收法测定的全身骨矿物质含量与通过外周定量计算机断层扫描测定的骨矿物质密度的相关性。
Correlation of total-body bone mineral content determined by dual-energy X-ray absorptiometry with bone mineral density determined by peripheral quantitative computed tomography.
作者信息
Revilla M, Cardenas J L, Hernández E R, Villa L F, Rico H
机构信息
Department of Medicine, Universidad de Alcalá de Henares, Madrid, Spain.
出版信息
Acad Radiol. 1995 Dec;2(12):1062-6. doi: 10.1016/s1076-6332(05)80514-8.
RATIONALE AND OBJECTIVES
We sought to determine the value of peripheral quantitative computed tomography (pQCT) in measuring bone mineral density.
METHODS
In 50 healthy, eugonodal premenopausal women, we correlated measurements of total bone mineral content (BMCTB), made with dual-energy X-ray absorptiometry (DXA), and bone mineral density, determined by pQCT.
RESULTS
The partial correlations, adjusted for weight and age, between BMCTB and cortical bone density, total bone density, and trabecular bone density were .71 (p < .0001), .63 (p < .0001), and .32 (p < .05), respectively.
CONCLUSION
These results and the advantages of pQCT--providing precise bone density determinations for trabecular and compact bone separately, having a high spatial resolution that allows a "compartmental" analysis of bone structure, having a low coefficient of variation, and having a minimal radiation dose (< 5 mrem)--confirm the adequacy of using this method for bone mass studies.
原理与目的
我们试图确定外周定量计算机断层扫描（pQCT）在测量骨矿物质密度方面的价值。
方法
在50名健康、性腺功能正常的绝经前女性中，我们将用双能X线吸收法（DXA）测量的总骨矿物质含量（BMCTB）与通过pQCT测定的骨矿物质密度进行了相关性分析。
结果
经体重和年龄校正后，BMCTB与皮质骨密度、总骨密度和小梁骨密度之间的偏相关性分别为0.71（p < 0.0001）、0.63（p < 0.0001）和0.32（p < 0.05）。
结论
这些结果以及pQCT的优势——能够分别精确测定小梁骨和密质骨的骨密度，具有高空间分辨率，可对骨结构进行“分区”分析，变异系数低，辐射剂量极小（< 5毫雷姆）——证实了使用该方法进行骨量研究的适用性。
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