Deo S, Knottenbelt J D
Trauma Unit, Groote Schuur Hospital, Cape Town, South Africa.
Eur J Emerg Med. 1994 Sep;1(3):111-4.
Experience with the use of midazolam in the resuscitation of severely injured patients is described. All 33 patients included in the study were given midazolam to allow endotracheal intubation and/or positive pressure ventilation in the resuscitation room, prior to transfer to the operating theatre or intensive care unit. Those with possible head injury were subjected to computed tomography of the head once stabilized. Adjuvant analgesia with an intravenous opiate was required in less than 40% of patients, and the amnesic properties of midazolam were found to be excellent. Cardiorespiratory side effects were not seen. Midazolam was found to be a safe and viable alternative to muscle relaxants, allowing endotracheal intubation and ventilation, in addition to other invasive procedures, to be carried out with minimal distress to the patient.
本文描述了使用咪达唑仑对重伤患者进行复苏的经验。该研究纳入的33例患者在转入手术室或重症监护病房之前，均在复苏室给予咪达唑仑以利于气管插管和/或正压通气。对可能存在头部损伤的患者，待病情稳定后进行头部计算机断层扫描。不到40%的患者需要静脉注射阿片类药物辅助镇痛，且发现咪达唑仑的遗忘效果极佳。未观察到心肺副作用。结果表明，咪达唑仑是肌肉松弛剂的一种安全可行的替代品，除其他侵入性操作外，还能在对患者造成最小痛苦的情况下进行气管插管和通气。
