Nödl F
Arch Dermatol Res (1975). 1976 Jun 21;255(3):237-43. doi: 10.1007/BF00561493.
Even without previous ray-treatment the mechanical effectivenes of the filtration ability of lymph-nodes may be reinforced by connective tissue growth around metastatic melanoma cells. On the other hand melanoma cells can pass this filter just because of the possibility to get into the lymph stream by means of wide lymphatics even within the first series of regional lymphatic ganglia. This is true also for passing the marginal lymphatic sinus and subsequent entering the vas efferens of the lymph-node. The therapeutical inferences of these observations are discussed.
即使没有先前的放射治疗，转移性黑色素瘤细胞周围结缔组织的生长也可能增强淋巴结过滤能力的机械有效性。另一方面，黑色素瘤细胞能够通过这个过滤器，正是因为它们有可能通过宽阔的淋巴管进入淋巴流，甚至在最初的一组区域淋巴结内。对于通过边缘淋巴窦并随后进入淋巴结的输出淋巴管来说也是如此。本文讨论了这些观察结果的治疗意义。
