Suppr超能文献

老年动脉粥样硬化性肾血管疾病:血管成形术加支架置入术与重建手术的比较

Atherosclerotic renovascular disease in the elderly: angioplasty with stenting versus reconstructive surgery.

作者信息

Bhandari S, Wilkinson A, Nicholson A, Farr M J, Sellars L

机构信息

Renal Unit, Hull Royal Infirmary, UK.

出版信息

Geriatr Nephrol Urol. 1997;7(2):87-94. doi: 10.1023/a:1008211909768.

Abstract

We reviewed our experience of surgical and radiological intervention in 43 patients between 1987 and 1994 with angiographic renovascular disease. We retrospectively compared the effect of angioplasty with stenting versus reconstructive surgery on renal function and blood pressure in those patients with significant atherosclerotic renovascular stenosis. Twenty patients with moderate/non ostial stenosis (less than 60% stenosis) and two with fibromuscular displasia underwent renal angioplasty only. Indications for intervention were refractory hypertension (n = 20), flash pulmonary oedema (n = 8) and/or renal salvage (n = 31). All patients were hypertensive. Angioplasty with stenting was performed in ten patients, (2 female, 8 male), mean age 69 years, 9 with bilateral disease. Plasma creatinine was greater than 240 mumol/L in seven patients. A unilateral procedure was performed in 9 patients. Unilateral reconstructive surgery was performed in eleven patients (4 female, 7 male), mean age 63 years. Plasma creatinine was greater than 240 mumol/L in eight patients. Ten had bilateral disease. In the angioplasty/stenting group there were three technical failure. The mortality rates in the angioplasty/stenting group and surgical group were 10% and 27% respectively. Fifty-one and 165 patient months had elapsed in the stenting and surgical groups respectively. Blood pressure fell in each group, mean decrease in mean arterial pressure (MAP) 16 mmHg (p = 0.025) and 30 mmHg (p < 0.01) respectively. Improvement or stabilisation of renal function was achieved in 67% and 91% of cases respectively. Two surgical patients were able to discontinue haemodialysis. The two methods of treatment appear to be equally effective in lowering blood pressure. Reconstructive surgery offers greater improvement in renal function with the possibility of withdrawal of dialysis, at the expense of a higher mortality rate.

摘要

我们回顾了1987年至1994年间对43例患有血管造影确诊的肾血管疾病患者进行手术和放射介入治疗的经验。我们回顾性比较了血管成形术加支架置入术与重建手术对那些患有严重动脉粥样硬化性肾血管狭窄患者的肾功能和血压的影响。20例中度/非开口处狭窄(狭窄程度小于60%)患者和2例纤维肌性发育异常患者仅接受了肾血管成形术。干预指征为顽固性高血压(n = 20)、急性肺水肿(n = 8)和/或挽救肾脏(n = 31)。所有患者均患有高血压。10例患者(2例女性,8例男性)接受了血管成形术加支架置入术,平均年龄69岁,9例患有双侧疾病。7例患者的血浆肌酐大于240 μmol/L。9例患者接受了单侧手术。11例患者(4例女性,7例男性)接受了单侧重建手术,平均年龄63岁。8例患者的血浆肌酐大于240 μmol/L。10例患有双侧疾病。在血管成形术/支架置入组中有3例技术失败。血管成形术/支架置入组和手术组的死亡率分别为10%和27%。支架置入组和手术组分别经过了51和165个患者月。两组患者的血压均下降,平均动脉压(MAP)平均下降分别为16 mmHg(p = 0.025)和30 mmHg(p < 0.01)。肾功能改善或稳定分别在67%和91%的病例中实现。2例手术患者能够停止血液透析。两种治疗方法在降低血压方面似乎同样有效。重建手术在改善肾功能方面效果更佳,有可能停止透析,但代价是死亡率较高。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验