Palomar J M, Bray D M, Grannis F W, Beaver P C
Arch Surg. 1976 Aug;111(8):909-11. doi: 10.1001/archsurg.1976.01360260077020.
Although infection with tissue nematodes is a significant health problem in many parts of the world, such cases are unusual in the continental United States. This report describes a case of Onchocerca volvulus infection, acquired by a 38-year-old female missionary in northern Brazil, that manifested as subcutaneous nodules in the groin and flank two years after the patient's return to the United States. A year previously, a wrong diagnosis of Wuchereria bancrofti was made at biopsy. At that time, treatment with diethylcarbamazine citrate had to be discontinued because of intense pruritus. Examination of a wet saline impression smear of a new biopsy specimen showed the adult worms to have regularly arranged outer annular ridges, which, together with the pruritus after treatment with diethylcarbamazine (a positive Mazzotti test), led to the diagnosis of onchocerciasis. Retreatment with diethylcarbamazine again caused pruritus, but this was tolerated as were subsequent treatments.
虽然组织线虫感染在世界许多地区是一个严重的健康问题，但在美国大陆此类病例并不常见。本报告描述了一例盘尾丝虫感染病例，一名38岁的女性传教士在巴西北部感染了这种疾病，在她返回美国两年后，腹股沟和侧腹出现了皮下结节。一年前，活检时误诊为班氏吴策线虫。当时，由于剧烈瘙痒，不得不停止使用枸橼酸乙胺嗪治疗。对新活检标本的湿盐水压印涂片检查显示，成虫有规则排列的外部环形嵴，再加上使用乙胺嗪治疗后出现瘙痒（马佐蒂试验阳性），从而诊断为盘尾丝虫病。再次使用乙胺嗪治疗再次引起瘙痒，但患者耐受了，后续治疗也是如此。
