Streptomycin and temperature sensitivity of colicin-like activity in Salmonella cultures.

Salmonellin production on agar was reduced by adding streptomycin or raising the incubation temperature to 44 degrees. Production of group 3b salcol was increased by incubation at 44 degrees and, for one producer only, by adding streptomycin. Production of the diffusible, nontransferable group 4 salcol and also of diffusible colicin V was reduced at 44 degrees. Group 1 salcol production was unaffected by raised temperature or streptomycin. Group 2 salcol production also was unaffected, except in salm+ transcipients of Arizona So116 where it was reduced along with salmonellin production by incubation at 44 degrees or addition of streptomycin.