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心脏再次移植前机械循环支持是否有帮助?

Is mechanical circulatory support helpful before cardiac retransplantation?

作者信息

Noirhomme P, d'Udekem Y, Jacquet L, El Khoury G, Verhelst R, Rubay J, Goenen M, Dion R

机构信息

Department of Cardiovascular and Thoracic Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

出版信息

Cardiovasc Surg. 1997 Dec;5(6):584-7. doi: 10.1016/s0967-2109(97)00076-8.

DOI:10.1016/s0967-2109(97)00076-8
PMID:9423943
Abstract

Ventricular assist devices are widely used as a bridge for cardiac transplantation patients. The purpose of the present study was to evaluate retrospectively, whether the use of ventricular assist devices could increase survival after early or late retransplantation. Over the past 10 years, 219 patients were transplanted in the authors' centre. Eight of 11 retransplanted patients required preoperative insertion of a ventricular assist device. Five assist systems were implanted in the early period after transplantation ( < 30 days) and three later after transplantation ( > 30 days). After early retransplantation, two patients survived and three died. All three late retransplantations were successful and all patients are still alive with a mean (s.d.) follow-up of 25(22) months. Ventricular assist devices are helpful for late retransplantation but do not improve poor survival after early retransplantation. Such devices should not be set up for early retransplantation.

摘要

心室辅助装置被广泛用作心脏移植患者的过渡手段。本研究的目的是回顾性评估使用心室辅助装置是否能提高早期或晚期再次移植后的生存率。在过去10年中,作者所在中心有219例患者接受了移植。11例再次移植患者中有8例需要在术前植入心室辅助装置。5套辅助系统在移植后早期(<30天)植入,3套在移植后期(>30天)植入。早期再次移植后,2例患者存活,3例死亡。所有3例晚期再次移植均成功,所有患者仍存活,平均(标准差)随访25(22)个月。心室辅助装置对晚期再次移植有帮助,但不能改善早期再次移植后的低生存率。不应为早期再次移植设置此类装置。

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Is mechanical circulatory support helpful before cardiac retransplantation?心脏再次移植前机械循环支持是否有帮助?
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Post-cardiac transplant survival after support with a continuous-flow left ventricular assist device: impact of duration of left ventricular assist device support and other variables.心脏移植后使用持续血流左心室辅助装置的生存情况:左心室辅助装置支持时间和其他变量的影响。
J Thorac Cardiovasc Surg. 2010 Jul;140(1):174-81. doi: 10.1016/j.jtcvs.2010.03.037. Epub 2010 May 5.

引用本文的文献

1
Mechanical circulatory support as a bridge to cardiac retransplantation: a single center experience.机械循环支持作为心脏再次移植的桥梁:单中心经验
J Heart Lung Transplant. 2015 Feb;34(2):161-6. doi: 10.1016/j.healun.2014.09.033. Epub 2014 Sep 28.