Zieniewicz K, Korta T, Pertkiewicz M, Krawczyk M, Michałowicz B, Karwowski A, Szczygiel B
Katedry i Kliniki Chirurgii Ogólnej i Chorób Watroby, AM w Warszawie.
Wiad Lek. 1997;50 Suppl 1 Pt 2:443-6.
The majority of liver transplanted patients are severely malnourished that increases the incidence of postoperative morbidity and mortality. The authors analysed the effects of nutritional support-total parenteral nutrition-in 11 adult orthotopic liver allograft recipients (9 women, 2 men) transplanted for chronic or acute liver failure in 1994-1997. 4.3-9.75 g of N/24h, 1200-1700 kcal in 1750-2750 ml, from 2-5th postoperative day was administered via central vein in all-in-one system for 4-46 days. Neither metabolic nor septic complications related to the nutrition were observed. The function of the transplanted liver was not impaired by the nutrition. One patient died in course of hepatic coma, 10 patients are alive and in good general condition (1-29 months). In conclusion, the total parenteral nutrition is safe, beneficial and thus recommended routine therapy in the treatment of the liver transplanted malnourished patients.
大多数肝移植患者严重营养不良,这增加了术后发病和死亡的发生率。作者分析了1994年至1997年期间接受慢性或急性肝衰竭原位肝移植的11例成年患者(9名女性,2名男性)营养支持——全胃肠外营养的效果。术后第2至5天,通过中心静脉在全合一系统中给予4.3 - 9.75g氮/24小时,1200 - 1700千卡热量于1750 - 2750毫升溶液中,持续4 - 46天。未观察到与营养相关的代谢或感染并发症。营养支持未损害移植肝脏的功能。1例患者死于肝昏迷,10例患者存活且一般状况良好(1至29个月)。总之,全胃肠外营养是安全、有益的,因此推荐作为肝移植营养不良患者治疗的常规疗法。