Burrell S J, Kingdom J C
Department of Obstetrics and Gynaecology, University College London Medical School, UK.
Curr Opin Obstet Gynecol. 1997 Dec;9(6):370-4.
In contrast to the reduction in perinatal mortality in high-risk pregnancies, screening of low-risk pregnancies with umbilical artery Doppler ultrasonography has shown no benefit. Advances in pathophysiology question the assumption that the placenta is hypoxic in fetal growth restriction, with absent end-diastolic frequencies in the umbilical artery. The timing of delivery in relation to Doppler findings is uncertain, and so trials that relate Doppler findings to neurodevelopmental outcome are necessary to refine the role of this technique in obstetric practice.
与高危妊娠围产期死亡率的降低形成对比的是，用脐动脉多普勒超声对低危妊娠进行筛查并未显示出益处。病理生理学的进展对胎儿生长受限情况下胎盘缺氧这一假设提出了质疑，而脐动脉舒张末期血流缺失正是基于该假设。与多普勒检查结果相关的分娩时机尚不确定，因此有必要进行将多普勒检查结果与神经发育结局相关联的试验，以明确该技术在产科实践中的作用。
