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对膀胱收缩功能不良的埃及血吸虫病患者逼尿肌的组织病理学研究。

Histopathological studies on detrusor muscle in schistosomiasis haematobium patients with poor bladder contractility.

作者信息

Ghobish A, Mangoud A M, Ramadan M E, Rifaat M M, Morsy T A

机构信息

Department of Urology, Faculty of Medicine, University of Suez Canal, Ismailia, Egypt.

出版信息

J Egypt Soc Parasitol. 1997 Dec;27(3):659-65.

PMID:9425812
Abstract

The electron microscopic structure of the detrusor muscle in schistosomiasis patients with poor bladder contractility as evaluated by urodynamic measures had been compared with normal detrusor muscle from non-schistosomiasis patients. In the patients with poor bladder contractility the detrusor was formed of muscle fibers which were smaller in size, widely separated by collagen and showed degenerative changes and hyalinosis. No evidence of smooth muscle hyperplasia, mitosis or fibroblastic proliferation was seen. This pathological changes in the bladder of schistosomiasis patients may explain the cause of poor contractility.

摘要

通过尿动力学测量评估膀胱收缩功能不佳的血吸虫病患者逼尿肌的电子显微镜结构,并与非血吸虫病患者的正常逼尿肌进行比较。在膀胱收缩功能不佳的患者中,逼尿肌由尺寸较小的肌纤维组成,这些肌纤维被胶原广泛分隔,并显示出退行性改变和玻璃样变性。未发现平滑肌增生、有丝分裂或成纤维细胞增殖的证据。血吸虫病患者膀胱的这种病理变化可能解释了收缩功能不佳的原因。

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