Abu-Madi M A
Department of Applied Sciences, Faculty of Technology, Qatar University, Doha-Qatar.
J Egypt Soc Parasitol. 1997 Dec;27(3):871-80.
The concurrent effects of aging on the lipid content of third-stage larvae (L3) of H.p. polygyrus and H.p. bakeri were described experimentally. It was shown that larval age was closely correlated with their infectivity. The infectivity of H. polygyrus in field and laboratory mice, as indicated by mean worm recovery, was significantly higher for one week old compared with 16 weeks old larvae. Image analysis has been used for the first time to quantify the lipid content of L3 of H. polygyrus with age. The proportion of lipid within infective larvae was reduced and their infectivity declined with age. It has also been found that larvae of H.p. polygyrus possess more lipid than H.p. bakeri suggesting that L3 larvae of H.p. polygyrus are physiologically different from those of H.p. bakeri and the additional lipid reserves assist in extending their survival time in the extremes of climatic conditions in the field.
通过实验描述了衰老对多氏旋毛虫和巴氏旋毛虫第三期幼虫（L3）脂质含量的同时影响。结果表明，幼虫年龄与其感染力密切相关。以平均蠕虫回收率表示，多氏旋毛虫在野外和实验室小鼠中的感染力，1周龄幼虫显著高于16周龄幼虫。首次使用图像分析来量化多氏旋毛虫L3随年龄变化的脂质含量。感染性幼虫体内的脂质比例随年龄增长而降低，其感染力也随之下降。还发现，多氏旋毛虫幼虫比巴氏旋毛虫拥有更多的脂质，这表明多氏旋毛虫的L3幼虫在生理上与巴氏旋毛虫不同，额外的脂质储备有助于它们在野外极端气候条件下延长存活时间。
