Losada A, Abad J P, Villasante A
Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), E-28049 Madrid, Spain.
Chromosoma. 1997 Dec;106(8):503-12. doi: 10.1007/s004120050272.
The structural analysis of a yeast artificial chromosome clone from Drosophila melanogaster enriched in dodecasatellite sequences has led us to find a new retrotransposon that we have called Circe. Moreover, this retrotransposon has allowed the isolation of a contig encompassing approximately 200 kb near the centromere of the Y chromosome, providing an entry point into a region from which very little sequence information has been obtained to date. The molecular characterization of the contig has shown the presence of HeT-A telomeric retrotransposons close to the centromere of the Y chromosome, suggesting a telocentric origin for this submetacentric chromosome.
对富含十二聚体卫星序列的黑腹果蝇酵母人工染色体克隆进行的结构分析，使我们发现了一种新的逆转座子，我们将其命名为喀耳刻（Circe）。此外，这种逆转座子使得一个包含Y染色体着丝粒附近约200 kb的重叠群得以分离，为进入一个迄今为止获得的序列信息极少的区域提供了切入点。对该重叠群的分子特征分析表明，在Y染色体着丝粒附近存在HeT-A端粒逆转座子，这表明这条亚中着丝粒染色体起源于端着丝粒染色体。
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