Skuba N D, Levkova N A
Biull Eksp Biol Med. 1979 Nov;88(11):621-3.
The relative weight of the heart and the thickness of muscular fibers in the left ventricular myocardium of rats were evaluated 70-91 and 120-227 days after creating stenosis of the abdominal portion of the aorta. Half of the animals were inoculated with cardiac type-specific embryonal RNA, the rest of the animals being intact. The data were treated by the variational statistical technique, by dispersion and mathematic analyses. Administration of RNA decreased the rate of myocardial hypertrophy development.
在大鼠腹主动脉狭窄形成后70 - 91天和120 - 227天,评估大鼠心脏的相对重量和左心室心肌肌纤维厚度。一半动物接种心脏特异性胚胎RNA,其余动物作为对照。数据采用变异统计技术、方差分析和数学分析方法处理。RNA的给予降低了心肌肥大的发展速率。